Goat Secondary Antibodies
Cayman Chemical C6 dIhydro CeramIded18 065mg
A metabolically inactive analog of C6 ceramide; has been used as a negative control in experiments investigating the biological activity of C6 ceramide
Cayman Chemical AfatInIbmaleate 250mg
An inhibitor of EGFR and ErbB2 (IC50s = 0.5 and 14 nM, respectively); increases the cytotoxicity of adriamycin in a concentration-dependent manner in multidrug-resistant A549T lung cancer cells overexpressing P-glycoprotein; reduces tumor growth in ErbB2-amplified NCI-N87 and NUGC4 gastric cancer mouse xenograft models at 20 mg/kg
Cayman Chemical GalectIn9ShortVarInthum50ug
Source: Recombinant N-terminal human IgG1 Fc-tagged galectin 9 expressed in HEK293 cells • Amino acids: 2-323 • MW: 61.8 kDa
Cayman Chemical PhosphoenolpyruvIc AcIdpota 1g
An enzyme substrate for glycolysis and gluconeogenesis pathways; metabolized to pyruvate by pyruvate kinase during glycolysis; formed from phosphoenolpyruvate carboxykinase-catalyzed oxaloacetate decarboxylation during gluconeogenesis
Cayman Chemical CetIrIzInhydrochlorIde 10g
A selective histamine H1 receptor antagonist (Ki = 10 nM); inhibits eosinophil chemotaxis and LTB4 release independent from H1 antagonism; inhibits aerosol histamine-induced bronchospasm in guinea pigs (ED50 = 100 μg/kg, p.o.)
Cayman Chemical 3-MethyladenIn 100mg
A specific inhibitor of PI3K activity and a widely used inhibitor of the autophagy; at 5 mM, inhibits protein degradation in rat hepatocytes by 65% and blocks class I, II, and III PI3Ks, including some downstream targets
Cayman Chemical TFIIHp52TFIIHbasltrnsc100uL
A GABAB receptor agonist increases latency to paw or tail withdrawal in the hot-plate test in mice at 1 and 3 mg/kg reduces the number of lever responses for alcohol in Sardinian alcohol-preferring rats at 3 mg/kg
Cayman Chemical PentadecafluoroctnoIc AcId 25g
A PFAS; chronic administration leads to accumulation in the kidney, liver, lung, heart, testes, and brain in rats at 5 and 20 mg/kg per day; is toxic to rats, inducing weight loss, sensitivity to external stimuli, lethargy, and hepatic inflammation at 20 mg/kg per day; found in marine life including lake trout, salmon, and whitefish, and as an environmental contaminant
Cayman Chemical n-NonylD-glucopyrnosIde 500mg
An anionic chiral surfactant; commonly used for the solubilization and crystallization of biological membrane proteins; has been used in the separation of drug enantiomers by micellar electrokinetic chromatography